Impact of an Exercise Intervention on DNA Methylation in Skeletal Muscle From First-Degree Relatives of Patients With Type 2 Diabetes

To identify epigenetic patterns, which may predispose to type 2 diabetes (T2D) due to a family history (FH) of the disease, we analyzed DNA methylation genome-wide in skeletal muscle from individuals with (FH(+)) or without (FH(−)) an FH of T2D. We found differential DNA methylation of genes in biol...

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Detalhes bibliográficos
Main Authors: Nitert, Marloes Dekker, Dayeh, Tasnim, Volkov, Peter, Elgzyri, Targ, Hall, Elin, Nilsson, Emma, Yang, Beatrice T., Lang, Stefan, Parikh, Hemang, Wessman, Ylva, Weishaupt, Holger, Attema, Joanne, Abels, Mia, Wierup, Nils, Almgren, Peter, Jansson, Per-Anders, Rönn, Tina, Hansson, Ola, Eriksson, Karl-Fredrik, Groop, Leif, Ling, Charlotte
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2012
Assuntos:
Genetics/Genomes/Proteomics/Metabolomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501844/
https://ncbi.nlm.nih.gov/pubmed/23028138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-1653
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