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Insights into erlotinib action in pancreatic cancer cells using a combined experimental and mathematical approach
AIM: To gain insights into the molecular action of erlotinib in pancreatic cancer (PC) cells. METHODS: Two PC cell lines, BxPC-3 and Capan-1, were treated with various concentrations of erlotinib, the specific mitogen-activated protein kinase kinase (MEK) inhibitor U0126, and protein kinase B (AKT)...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Baishideng Publishing Group Co., Limited
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3501770/ https://ncbi.nlm.nih.gov/pubmed/23180942 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v18.i43.6226 |
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