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Distinct antifibrogenic effects of erlotinib, sunitinib and sorafenib on rat pancreatic stellate cells
AIM: To study if three clinically available small molecule kinase inhibitors (SMI), erlotinib, sunitinib and sorafenib, exert antifibrogenic effects on pancreatic stellate cells (PSC) and analyze the basis of their action. METHODS: Cultured rat PSC were exposed to SMI. Cell proliferation and viabili...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Baishideng Publishing Group Inc
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4069318/ https://ncbi.nlm.nih.gov/pubmed/24976727 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v20.i24.7914 |
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