Lack of CAK complex accumulation at DNA damage sites in XP-B and XP-B/CS fibroblasts reveals differential regulation of CAK anchoring to core TFIIH by XPB and XPD helicases during nucleotide excision repair

Transcription factor II H (TFIIH) is composed of core TFIIH and Cdk-activating kinase (CAK) complexes. Besides transcription, TFIIH also participates in nucleotide excision repair (NER), verifying DNA lesions through its helicase components XPB and XPD. The assembly state of TFIIH is known to be aff...

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Bibliografiska uppgifter
Huvudupphovsmän: Zhu, Qianzheng, Wani, Gulzar, Sharma, Nidhi, Wani, Altaf
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501591/
https://ncbi.nlm.nih.gov/pubmed/23083890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2012.09.003
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