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Comparison of mutation findings in ZIC2 between microform and classical holoprosencephaly in a Brazilian cohort

BACKGROUND: Holoprosencephaly is the most frequent congenital malformation of the forebrain in humans. It is anatomically classified by the relative degree of abnormal formation and separation of the developing midline central nervous system. Mutations of ZIC2 are the second most common heterozygous...

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Autors principals: Ribeiro, Lucilene A., Roessler, Erich, Hu, Ping, Pineda-Alvarez, Daniel E., Zhou, Nan, Jones, MaryPat, Chandrasekharappa, Settara, Richieri-Costa, Antonio, Muenke, Maximilian
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501551/
https://ncbi.nlm.nih.gov/pubmed/22847929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bdra.23047
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