SUZ12 promotes human epithelial ovarian cancer by suppressing apoptosis via silencing HRK

Epithelial ovarian cancer (EOC) ranks first as the cause of death for gynecological cancers in the United States. SUZ12 is a component of the polycomb repressive complex 2 (PRC2) and is essential for PRC2-mediated gene silencing by generating trimethylation on lysine 27 residue of histone H3 (H3K27M...

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Detalhes bibliográficos
Main Authors: Li, Hua, Cai, Qi, Wu, Hong, Vathipadiekal, Vinod, Dobbin, Zachary C., Li, Tianyu, Hua, Xiang, Landen, Charles N., Birrer, Michael J., Sánchez-Beato, Margarita, Zhang, Rugang
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501543/
https://ncbi.nlm.nih.gov/pubmed/22964433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-12-0335
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