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Tissue Transglutaminase Constitutively Activates HIF-1α Promoter and Nuclear Factor-κB via a Non-Canonical Pathway

Constitutive activation of nuclear factor kappa B (NF-κB) has been linked with carcinogenesis and cancer progression, including metastasis, chemoresistance, and radiation resistance. However, the molecular mechanisms that result in constitutive activation of NF-κB are poorly understood. Here we show...

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Detalhes bibliográficos
Main Authors: Kumar, Santosh, Mehta, Kapil
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501523/
https://ncbi.nlm.nih.gov/pubmed/23185316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049321
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