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A Novel Bioassay for the Activity Determination of Therapeutic Human Brain Natriuretic Peptide (BNP)

BACKGROUND: Recombinant human brain natriuretic peptide (rhBNP) is an important peptide-based therapeutic drug indicated for the treatment of acute heart failure. Accurate determination of the potency of therapeutic rhBNP is crucial for the safety and efficacy of the drug. The current bioassay invol...

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Main Authors: Yu, Lei, Rao, Chunming, Shi, Xinchang, Li, Yonghong, Gao, Kai, Li, Xuguang, Wang, Junzhi
格式: Artigo
語言:Inglês
出版: Public Library of Science 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501489/
https://ncbi.nlm.nih.gov/pubmed/23185490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049934
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