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Bioactivity Determination of a Therapeutic Recombinant Human Keratinocyte Growth Factor by a Validated Cell-based Bioassay

The therapeutic recombinant human keratinocyte growth factor 1 (rhKGF-1) was approved by the FDA for oral mucositis resulting from hematopoietic stem cell transplantation for hematological malignancies in 2004. However, no recommended bioassay for rhKGF-1 bioactivity has been recorded in the U.S. Ph...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Yao, Wenrong, Guo, Ying, Qin, Xi, Yu, Lei, Shi, Xinchang, Liu, Lan, Zhou, Yong, Hu, Jinpan, Rao, Chunming, Wang, Junzhi
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6412437/
https://ncbi.nlm.nih.gov/pubmed/30769959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24040699
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