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Allele Specific Expression of the Transthyretin Gene in Swedish Patients with Hereditary Transthyretin Amyloidosis (ATTR V30M) Is Similar between the Two Alleles

BACKGROUND: Hereditary transthyretin (TTR) amyloidosis (ATTR) is an autosomal dominant disease characterized by extracellular deposits of amyloid fibrils composed of misfolded TTR. The differences in penetrance and age at onset are vast, both between and within populations, with a generally late ons...

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Detalhes bibliográficos
Main Authors: Norgren, Nina, Hellman, Urban, Ericzon, Bo Göran, Olsson, Malin, Suhr, Ole B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501482/
https://ncbi.nlm.nih.gov/pubmed/23185504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049981
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