Congenital B cell lymphocytosis explained by novel germline CARD11 mutations

Nuclear factor-κB (NF-κB) controls genes involved in normal lymphocyte functions, but constitutive NF-κB activation is often associated with B cell malignancy. Using high-throughput whole transcriptome sequencing, we investigated a unique family with hereditary polyclonal B cell lymphocytosis. We fo...

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Bibliografiset tiedot
Päätekijät: Snow, Andrew L., Xiao, Wenming, Stinson, Jeffrey R., Lu, Wei, Chaigne-Delalande, Benjamin, Zheng, Lixin, Pittaluga, Stefania, Matthews, Helen F., Schmitz, Roland, Jhavar, Sameer, Kuchen, Stefan, Kardava, Lela, Wang, Wei, Lamborn, Ian T., Jing, Huie, Raffeld, Mark, Moir, Susan, Fleisher, Thomas A., Staudt, Louis M., Su, Helen C., Lenardo, Michael J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Rockefeller University Press 2012
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501355/
https://ncbi.nlm.nih.gov/pubmed/23129749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20120831
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