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Overcoming resistance and restoring sensitivity to HER2-targeted therapies in breast cancer
BACKGROUND: Approximately 15%–23% of breast cancers overexpress human epidermal growth factor receptor 2 (HER2), which leads to the activation of signaling pathways that stimulate cell proliferation and survival. HER2-targeted therapy has substantially improved outcomes in patients with HER2-positiv...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3501233/ https://ncbi.nlm.nih.gov/pubmed/22865781 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/annonc/mds200 |
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