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Role of mTOR Inhibition in Preventing Resistance and Restoring Sensitivity to Hormone-Targeted and HER2-Targeted Therapies in Breast Cancer

Even with hormone-targeted and human epidermal growth factor receptor 2 (HER2)–targeted anticancer agents, intrinsic resistance or acquired resistance are common occurrences in estrogen receptor–positive and HER2-positive breast cancers, respectively. Potential mechanisms for resistance to targeted...

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Detalhes bibliográficos
Autor principal: Mayer, Ingrid
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774138/
https://ncbi.nlm.nih.gov/pubmed/23604238
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