Glutathionylation State of Uncoupling Protein-2 and the Control of Glucose-stimulated Insulin Secretion

The role of reactive oxygen species (ROS) in glucose-stimulated insulin release remains controversial because ROS have been shown to both amplify and impede insulin release. In regard to preventing insulin release, ROS activates uncoupling protein-2 (UCP2), a mitochondrial inner membrane protein tha...

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Detalhes bibliográficos
Main Authors: Mailloux, Ryan J., Fu, Accalia, Robson-Doucette, Christine, Allister, Emma M., Wheeler, Michael B., Screaton, Robert, Harper, Mary-Ellen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Bioenergetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501076/
https://ncbi.nlm.nih.gov/pubmed/23035124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.393538
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