Substrate-bound Crystal Structures Reveal Features Unique to Mycobacterium tuberculosis N-Acetyl-glucosamine 1-Phosphate Uridyltransferase and a Catalytic Mechanism for Acetyl Transfer

N-Acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), a bifunctional enzyme involved in bacterial cell wall synthesis is exclusive to prokaryotes. GlmU, now recognized as a promising target to develop new antibacterial drugs, catalyzes two key reactions: acetyl transfer and uridyl transfer at t...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Jagtap, Pravin Kumar Ankush, Soni, Vijay, Vithani, Neha, Jhingan, Gagan Deep, Bais, Vaibhav Singh, Nandicoori, Vinay Kumar, Prakash, Balaji
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501063/
https://ncbi.nlm.nih.gov/pubmed/22969087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.390765
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados