Golgi Phosphoprotein 3 Determines Cell Binding Properties under Dynamic Flow by Controlling Golgi Localization of Core 2 N-Acetylglucosaminyltransferase 1

Core 2 N-acetylglucosaminyltransferase 1 (C2GnT1) is a key enzyme participating in the synthesis of core 2-associated sialyl Lewis x (C2-O-sLe(x)), a ligand involved in selectin-mediated leukocyte trafficking and cancer metastasis. To accomplish that, C2GnT1 needs to be localized to the Golgi and th...

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Bibliographic Details
Main Authors: Ali, Mohamed F., Chachadi, Vishwanath B., Petrosyan, Armen, Cheng, Pi-Wan
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2012
Subjects:
Glycobiology and Extracellular Matrices
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501027/
https://ncbi.nlm.nih.gov/pubmed/23027862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.346528
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