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Keratin 1 Plays a Critical Role in Golgi Localization of Core 2 N-Acetylglucosaminyltransferase M via Interaction with Its Cytoplasmic Tail

Core 2 N-acetylglucosaminyltransferase 2/M (C2GnT-M) synthesizes all three β6GlcNAc branch structures found in secreted mucins. Loss of C2GnT-M leads to development of colitis and colon cancer. Recently we have shown that C2GnT-M targets the Golgi at the Giantin site and is recycled by binding to no...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Petrosyan, Armen, Ali, Mohamed F., Cheng, Pi-Wan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358263/
https://ncbi.nlm.nih.gov/pubmed/25605727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.618702
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