Analgesic activity of the naturally occurring heptapeptide [Met]enkephalin-Arg6-Phe7.
[Met]Enkephalin-Arg6-Phe7 is an opiate-like peptide normally found in the the adrenal gland and brain that has analgesic (antinociceptive) activity when administered directly into the cerebral ventricles of mice. On a molar basis, [Met]-enkephalin-Arg6-Phe7, with a median effective dose (ED50) of 38...
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| 發表在: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
1980
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC350091/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6933569/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.9.5512 |
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