Analgesic activity of the naturally occurring heptapeptide [Met]enkephalin-Arg6-Phe7.

[Met]Enkephalin-Arg6-Phe7 is an opiate-like peptide normally found in the the adrenal gland and brain that has analgesic (antinociceptive) activity when administered directly into the cerebral ventricles of mice. On a molar basis, [Met]-enkephalin-Arg6-Phe7, with a median effective dose (ED50) of 38...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Inturrisi, C E, Umans, J G, Wolff, D, Stern, A S, Lewis, R V, Stein, S, Udenfriend, S
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1980
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC350091/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6933569/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.9.5512
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