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Selective killing of normal or neoplastic B cells by antibodies coupled to the A chain of ricin.

Highly specific antibodies (affinity-purified or hybridoma) directed against cell surface immunoglobulins on normal or neoplastic murine B lymphocytes were covalently coupled to the A chain of the plant toxin ricin. Such conjugates containing antibodies specific for IgM, for either of the two alloty...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Krolick, K A, Villemez, C, Isakson, P, Uhr, J W, Vitetta, E S
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1980
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC350070/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6968912/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.9.5419
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