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Selective killing of normal or neoplastic B cells by antibodies coupled to the A chain of ricin.

Highly specific antibodies (affinity-purified or hybridoma) directed against cell surface immunoglobulins on normal or neoplastic murine B lymphocytes were covalently coupled to the A chain of the plant toxin ricin. Such conjugates containing antibodies specific for IgM, for either of the two alloty...

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Autors principals: Krolick, K A, Villemez, C, Isakson, P, Uhr, J W, Vitetta, E S
Format: Artigo
Idioma:Inglês
Publicat: 1980
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC350070/
https://ncbi.nlm.nih.gov/pubmed/6968912
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