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Conservation and evolutionary divergence in the activity of receptor-regulated smads

BACKGROUND: Activity of the Transforming growth factor-β (TGFβ) pathway is essential to the establishment of body axes and tissue differentiation in bilaterians. Orthologs for core pathway members have been found in all metazoans, but uncertain homology of the body axes and tissues patterned by thes...

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Detalhes bibliográficos
Main Authors: Sorrentino, Gina M, Gillis, William Q, Oomen-Hajagos, Jamina, Thomsen, Gerald H
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3500652/
https://ncbi.nlm.nih.gov/pubmed/23020873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2041-9139-3-22
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