Interleukin-6 Knockout Prevents Angiotensin II Hypertension: Role of Renal Vasoconstriction and JAK2/STAT3 Activation

Chronic angiotensin II (AngII) infusion stimulates IL-6 release, and we and others have shown that preventing the increase in IL-6 significantly attenuates AngII hypertension. This study measured renal blood flow (RBF) chronically, using Transonic flow probes in wildtype (WT) and IL-6 knockout (KO)...

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Bibliografiske detaljer
Main Authors: Brands, Michael W., Banes-Berceli, Amy K.L., Inscho, Edward W., Al-Azawi, Hind, Allen, Ashlyn J., Labazi, Hicham
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3500610/
https://ncbi.nlm.nih.gov/pubmed/20921429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.110.158071
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