Cytotoxic effects of Mn(III) N-alkylpyridylporphyrins in the presence of cellular reductant, ascorbate

Due to the ability to easily accept and donate electrons Mn(III) N-alkylpyridylporphyrins (MnPs) can dismute O(2)(˙−), reduce peroxynitrite, but also generate reactive species and behave as pro-oxidants if conditions favour such action. Herein two ortho isomers, MnTE-2-PyP(5+), MnTnHex-2-PyP(5+), an...

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Detalhes bibliográficos
Main Authors: Ye, Xiaodong, Fels, Diane, Tovmasyan, Artak, Aird, Katherine M., Dedeugd, Casey, Allensworth, Jennifer L., Kos, Ivan, Park, Won, Spasojevic, Ivan, Devi, Gayathri R., Dewhirst, Mark W., Leong, Kam W., Batinic-Haberle, Ines
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3500602/
https://ncbi.nlm.nih.gov/pubmed/21859376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10715762.2011.616199
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