Fatp1 Deficiency Affects Retinal Light Response and Dark Adaptation, and Induces Age-Related Alterations

FATP1 is involved in lipid transport into cells and in intracellular lipid metabolism. We showed previously that this protein interacts with and inhibits the limiting-step isomerase of the visual cycle RPE65. Here, we aimed to analyze the effect of Fatp1-deficiency in vivo on the visual cycle, struc...

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Hauptverfasser: Chekroud, Karim, Guillou, Laurent, Grégoire, Stephane, Ducharme, Gilles, Brun, Emilie, Cazevieille, Chantal, Bretillon, Lionel, Hamel, Christian P., Brabet, Philippe, Pequignot, Marie O.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3500375/
https://ncbi.nlm.nih.gov/pubmed/23166839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050231
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