FATP1 Inhibits 11-cis Retinol Formation via Interaction with the Visual Cycle Retinoid Isomerase RPE65 and Lecithin:Retinol Acyltransferase

The isomerization of all-trans retinol (vitamin A) to 11-cis retinol in the retinal pigment epithelium (RPE) is a key step in the visual process for the regeneration of the visual pigment chromophore, 11-cis retinal. LRAT and RPE65 are recognized as the minimal isomerase catalytic components. Howeve...

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Detalhes bibliográficos
Main Authors: Guignard, Thomas J. P., Jin, Minghao, Pequignot, Marie O., Li, Songhua, Chassigneux, Yolaine, Chekroud, Karim, Guillou, Laurent, Richard, Eric, Hamel, Christian P., Brabet, Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881799/
https://ncbi.nlm.nih.gov/pubmed/20356843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.064329
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