Sensitivity to Lysosome-Dependent Cell Death Is Directly Regulated by Lysosomal Cholesterol Content

Alterations in lipid homeostasis are implicated in several neurodegenerative diseases, although the mechanisms responsible are poorly understood. We evaluated the impact of cholesterol accumulation, induced by U18666A, quinacrine or mutations in the cholesterol transporting Niemann-Pick disease type...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Appelqvist, Hanna, Sandin, Linnea, Björnström, Karin, Saftig, Paul, Garner, Brett, Öllinger, Karin, Kågedal, Katarina
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2012
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3500374/
https://ncbi.nlm.nih.gov/pubmed/23166840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050262
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