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A Novel Role of Human Holliday Junction Resolvase GEN1 in the Maintenance of Centrosome Integrity
The maintenance of genomic stability requires accurate genome replication, repair of DNA damage, and the precise segregation of chromosomes in mitosis. GEN1 possesses Holliday junction resolvase activity in vitro and presumably functions in homology driven repair of DNA double strand breaks. However...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3500319/ https://ncbi.nlm.nih.gov/pubmed/23166748 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049687 |
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