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Human Holliday junction resolvase GEN1 uses a chromodomain for efficient DNA recognition and cleavage
Holliday junctions (HJs) are key DNA intermediates in homologous recombination. They link homologous DNA strands and have to be faithfully removed for proper DNA segregation and genome integrity. Here, we present the crystal structure of human HJ resolvase GEN1 complexed with DNA at 3.0 Å resolution...
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| Yayımlandı: | eLife |
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| Asıl Yazarlar: | , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
eLife Sciences Publications, Ltd
2015
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5039027/ https://ncbi.nlm.nih.gov/pubmed/26682650 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.12256 |
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