Processing of the precursor to corticotropin and beta-lipotropin in humans.

The biosynthesis of human corticotropin (ACTH) was studied in organ culture of pituitary adenomas and by translating mRNA from an ectopic ACTH-producing tumor in a cell-free system. Peptides similar to human ACTH, beta-lipotropin, and the amino-terminal glycopeptide are cleaved from a common precurs...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Miller, W L, Johnson, L K, Baxter, J D, Roberts, J L
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1980
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC350027/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6254067/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.9.5211
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