Processing of the precursor to corticotropin and beta-lipotropin in humans.
The biosynthesis of human corticotropin (ACTH) was studied in organ culture of pituitary adenomas and by translating mRNA from an ectopic ACTH-producing tumor in a cell-free system. Peptides similar to human ACTH, beta-lipotropin, and the amino-terminal glycopeptide are cleaved from a common precurs...
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| Izdano u: | Proc Natl Acad Sci U S A |
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| Glavni autori: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
1980
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC350027/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6254067/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.9.5211 |
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