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Functional nsSNPs from carcinogenesis-related genes expressed in breast tissue: Potential breast cancer risk alleles and their distribution across human populations

Although highly penetrant alleles of BRCA1 and BRCA2 have been shown to predispose to breast cancer, the majority of breast cancer cases are assumed to result from the presence of low-moderate penetrant alleles and environmental carcinogens. Non-synonymous single nucleotide polymorphisms (nsSNPs) ar...

詳細記述

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書誌詳細
主要な著者: Savas, Sevtap, Schmidt, Steffen, Jarjanazi, Hamdi, Ozcelik, Hilmi
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2006
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3500178/
https://ncbi.nlm.nih.gov/pubmed/16595073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-7364-2-5-287
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