Acyclovir inhibition of Epstein-Barr virus replication.

Acyclovir [9-(2-hydroxyethoxymethyl)guanine] triphosphate inhibits Epstein-Barr virus (EBV)-associated DNA polymerase (DNA nucleotidyltransferase; EC 2.7.7.7) to a greater extent than it inhibits host alpha and beta DNA polymerases. The affinity of the compound for viral polymerase is 100-fold highe...

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Bibliografiske detaljer

Udgivet i:	Proc Natl Acad Sci U S A
Principais autores:	Datta, A K, Colby, B M, Shaw, J E, Pagano, J S
Format:	Artigo
Sprog:	Inglês
Udgivet:	National Academy of Sciences 1980
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC350017/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6254061/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.9.5163
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