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The role of CTCF binding sites in the 3′ immunoglobulin heavy chain regulatory region

The immunoglobulin heavy chain locus undergoes a series of DNA rearrangements and modifications to achieve the construction and expression of individual antibody heavy chain genes in B cells. These events affect variable regions, through VDJ joining and subsequent somatic hypermutation, and constant...

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Hlavní autor: Birshtein, Barbara K.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499808/
https://ncbi.nlm.nih.gov/pubmed/23162572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2012.00251
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