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Epigenetic Regulation of Individual Modules of the immunoglobulin heavy chain locus 3′ Regulatory Region
The Igh locus undergoes an amazing array of DNA rearrangements and modifications during B cell development. During early stages, the variable region gene is constructed from constituent variable (V), diversity (D), and joining (J) segments (VDJ joining). B cells that successfully express an antibody...
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| Auteur principal: | |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Frontiers Media S.A.
2014
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| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4000994/ https://ncbi.nlm.nih.gov/pubmed/24795714 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2014.00163 |
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