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An attempt to distinguish between the actions of neuromuscular blocking drugs on the acetylcholine receptor and on its associated ionic channel

The effects of lobeline and tubocurarine on the voltage-clamped endplates of frog sartorius and cutaneous pectoris muscles were examined at room temperature (20-23°C). Like tubocurarine, lobeline causes nondepolarizing neuromuscular blockade. The half-time of decay (t(½)) of endplate currents (e.p.c...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Lambert, Jeremy J., Volle, Robert L., Henderson, Edward G.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1980
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349978/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6254051/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.8.5003
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