An attempt to distinguish between the actions of neuromuscular blocking drugs on the acetylcholine receptor and on its associated ionic channel

The effects of lobeline and tubocurarine on the voltage-clamped endplates of frog sartorius and cutaneous pectoris muscles were examined at room temperature (20-23°C). Like tubocurarine, lobeline causes nondepolarizing neuromuscular blockade. The half-time of decay (t(½)) of endplate currents (e.p.c...

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Bibliographic Details

Published in:	Proc Natl Acad Sci U S A
Main Authors:	Lambert, Jeremy J., Volle, Robert L., Henderson, Edward G.
Format:	Artigo
Language:	Inglês
Published:	National Academy of Sciences 1980
Subjects:	Biological Sciences: Neurobiology
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349978/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6254051/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.8.5003
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