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Stereocontrolled Synthesis of α-Amino-α′-alkoxy Ketones by a Copper-Catalyzed Cross-Coupling of Peptidic Thiol Esters and α-Alkoxyalkylstannanes

[Image: see text] A stereocontrolled synthesis of α-amino-α′-alkoxy ketones is described. This pH-neutral copper(I) thiophene-2-carboxylate (CuTC)-catalyzed cross-coupling of amino acid thiol esters and chiral nonracemic α-alkoxyalkylstannanes gives α-amino-α′-alkoxy ketones in good to excellent yie...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Li, Hao, He, Anyu, Falck, John R., Liebeskind, Lanny S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499733/
https://ncbi.nlm.nih.gov/pubmed/21675755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol201330j
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