Nalaganje...
Plk1 is upregulated in androgen-insensitive prostate cancer cells and its inhibition leads to necroptosis
Castration-resistant prostate cancer (PCa) is refractory to hormone therapy and new strategies for treatment are urgently needed. We found that androgen-insensitive (AI) PCa cells, LNCaP-AI, are reprogrammed to upregulate the mitotic kinase Plk1 and other M phase cell cycle proteins, which may under...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3499666/ https://ncbi.nlm.nih.gov/pubmed/22890325 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.309 |
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