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Molecular determinants of ovarian cancer chemoresistance: new insights into an old conundrum

Ovarian cancer is the most lethal gynecological malignancy. Cisplatin and its derivatives are first-line chemotherapeutics, and their resistance is a major hurdle in successful ovarian cancer treatment. Understanding the molecular dysregulation underlying chemoresistance is important for enhancing t...

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Detalhes bibliográficos
Main Authors: Ali, Ahmed Y, Farrand, Lee, Kim, Ji Young, Byun, Sanguine, Suh, Jeong-Yong, Lee, Hyong Joo, Tsang, Benjamin K
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Inc 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499654/
https://ncbi.nlm.nih.gov/pubmed/23050965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1749-6632.2012.06734.x
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