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Validation of Response Function Construction and Probing Heterogeneous Protein Hydration by Intrinsic Tryptophan
Protein solvation dynamics usually occur on multiple time scales with site specificity and the characterization of such heterogeneous dynamics requires a convenient optical probe. We proposed a tryptophan methodology and with site-directed mutagenesis we can use a tryptophan scan to probe any desira...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3499651/ https://ncbi.nlm.nih.gov/pubmed/23075091 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp305118n |
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