Therapeutic Helminth Infection of Macaques with Idiopathic Chronic Diarrhea Alters the Inflammatory Signature and Mucosal Microbiota of the Colon

Idiopathic chronic diarrhea (ICD) is a leading cause of morbidity amongst rhesus monkeys kept in captivity. Here, we show that exposure of affected animals to the whipworm Trichuris trichiura led to clinical improvement in fecal consistency, accompanied by weight gain, in four out of the five treate...

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Detalhes bibliográficos
Main Authors: Broadhurst, Mara Jana, Ardeshir, Amir, Kanwar, Bittoo, Mirpuri, Julie, Gundra, Uma Mahesh, Leung, Jacqueline M., Wiens, Kirsten E., Vujkovic-Cvijin, Ivan, Kim, Charlie C., Yarovinsky, Felix, Lerche, Nicholas W., McCune, Joseph M., Loke, P'ng
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499566/
https://ncbi.nlm.nih.gov/pubmed/23166490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003000
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