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Finite Adaptation and Multistep Moves in the Metropolis-Hastings Algorithm for Variable Selection in Genome-Wide Association Analysis

High-dimensional datasets with large amounts of redundant information are nowadays available for hypothesis-free exploration of scientific questions. A particular case is genome-wide association analysis, where variations in the genome are searched for effects on disease or other traits. Bayesian va...

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Autori principali: Peltola, Tomi, Marttinen, Pekka, Vehtari, Aki
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499564/
https://ncbi.nlm.nih.gov/pubmed/23166669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049445
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