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Bayesian Variable Selection in Searching for Additive and Dominant Effects in Genome-Wide Data

Although complex diseases and traits are thought to have multifactorial genetic basis, the common methods in genome-wide association analyses test each variant for association independent of the others. This computational simplification may lead to reduced power to identify variants with small effec...

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Main Authors: Peltola, Tomi, Marttinen, Pekka, Jula, Antti, Salomaa, Veikko, Perola, Markus, Vehtari, Aki
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3250410/
https://ncbi.nlm.nih.gov/pubmed/22235263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029115
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