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Linkage of alpha G-Philadelphia to alpha-thalassemia in African-Americans .

We have studied the inheritance of the alpha-chain hemoglobin variant Hb G-Philadelphia (alpha 2(68 Asn leads to Lys)Beta 2) in two African-American families. Expression of the alpha-globin loci was monitored by the percentage of Hb G in these individuals. The variant represented approximately 33% o...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Surrey, S, Ohene-Frempong, K, Rappaport, E, Atwater, J, Schwartz, E
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1980
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349953/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6933536/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.8.4885
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