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Subtype- and antigenic site-specific differences in biophysical influences on evolution of influenza virus hemagglutinin
BACKGROUND: Influenza virus undergoes rapid evolution by both antigenic shift and antigenic drift. Antibodies, particularly those binding near the receptor-binding site of hemagglutinin (HA) or the neuraminidase (NA) active site, are thought to be the primary defense against influenza infection, and...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3499391/ https://ncbi.nlm.nih.gov/pubmed/22569196 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-9-91 |
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