Integrin αvβ3 and CD44 pathways in metastatic prostate cancer cells support osteoclastogenesis via a Runx2/Smad 5/receptor activator of NF-κB ligand signaling axis

BACKGROUND: Bone loss and pathological fractures are common skeletal complications associated with androgen deprivation therapy and bone metastases in prostate cancer patients. We have previously demonstrated that prostate cancer cells secrete receptor activator of NF-kB ligand (RANKL), a protein es...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Gupta, Aditi, Cao, Wei, Chellaiah, Meenakshi A
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2012
Aiheet:
Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499378/
https://ncbi.nlm.nih.gov/pubmed/22966907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-11-66
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia