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Heterogeneous epigenetic regulation of TIMP3 in prostate cancer

Tissue inhibitor of metalloproteinase-3 (TIMP3) is a tumor suppressor gene frequently downregulated in prostate cancer. The mechanisms involved in TIMP3 transcriptional repression are not fully understood, but evidence suggests that promoter hypermethylation may not be the predominant epigenetic alt...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Shinojima, Toshiaki, Yu, Qiang, Huang, Sharon K., Li, Michelle, Mizuno, Ryuichi, Liu, Edison T., Hoon, Dave S.B., Lessard, Laurent
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Landes Bioscience 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499329/
https://ncbi.nlm.nih.gov/pubmed/23023649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.22333
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