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Heterogeneous epigenetic regulation of TIMP3 in prostate cancer
Tissue inhibitor of metalloproteinase-3 (TIMP3) is a tumor suppressor gene frequently downregulated in prostate cancer. The mechanisms involved in TIMP3 transcriptional repression are not fully understood, but evidence suggests that promoter hypermethylation may not be the predominant epigenetic alt...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Landes Bioscience
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3499329/ https://ncbi.nlm.nih.gov/pubmed/23023649 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.22333 |
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