Heterogeneous epigenetic regulation of TIMP3 in prostate cancer

Tissue inhibitor of metalloproteinase-3 (TIMP3) is a tumor suppressor gene frequently downregulated in prostate cancer. The mechanisms involved in TIMP3 transcriptional repression are not fully understood, but evidence suggests that promoter hypermethylation may not be the predominant epigenetic alt...

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Detaylı Bibliyografya
Asıl Yazarlar: Shinojima, Toshiaki, Yu, Qiang, Huang, Sharon K., Li, Michelle, Mizuno, Ryuichi, Liu, Edison T., Hoon, Dave S.B., Lessard, Laurent
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Landes Bioscience 2012
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499329/
https://ncbi.nlm.nih.gov/pubmed/23023649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.22333
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