Heterogeneous epigenetic regulation of TIMP3 in prostate cancer

Tissue inhibitor of metalloproteinase-3 (TIMP3) is a tumor suppressor gene frequently downregulated in prostate cancer. The mechanisms involved in TIMP3 transcriptional repression are not fully understood, but evidence suggests that promoter hypermethylation may not be the predominant epigenetic alt...

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Bibliografske podrobnosti
Main Authors: Shinojima, Toshiaki, Yu, Qiang, Huang, Sharon K., Li, Michelle, Mizuno, Ryuichi, Liu, Edison T., Hoon, Dave S.B., Lessard, Laurent
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2012
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499329/
https://ncbi.nlm.nih.gov/pubmed/23023649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.22333
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